Informed Surgery

ACDF uses a spacer (cage or bone graft) where the disc was, usually with a small plate and screws, plus bone graft material. Cervical disc replacement uses an artificial disc instead. Listed alphabetically.

Several companies have FDA-approved artificial cervical discs. Approval for one level doesn't mean approval for two. Ask which device your surgeon uses and what it's approved for.

Listing a company or product is not an endorsement, and no company pays to be listed. This list may be incomplete. Compiled November 2026 from FDA records, company pages and trade press.

ATEC (Alphatec)

Cervical fusion systems

What they make for this
Cervical cages, plates and approach systems.

Sources: Company site

DePuy Synthes (J&J MedTech)

Cervical fusion systems

What they make for this
Cervical plates, cages and bone graft products.

Sources: Company site

Globus Medical (including NuVasive)

Cervical fusion and disc replacement

What they make for this
Cervical cages and plates, and artificial cervical discs.

Sources: Company site

Highridge Medical

Mobi-C cervical disc

What they make for this
Artificial cervical disc approved for one and two levels in the US.

Sources: Company site

Medtronic

Cervical fusion and Prestige LP disc

What they make for this
Cervical plates, cages and the Prestige LP artificial cervical disc.

Sources: Company site

Synergy Spine Solutions

Synergy Disc

What they make for this
An artificial cervical disc with a built-in angled core designed to restore neck alignment.
US status
Approved by the FDA on February 26, 2026, for single-level use from C3 to C7.
Evidence note
The approval study compared it with an older ACDF group from a separate trial rather than randomizing patients.

Sources: FDA record P250028 · Becker's Spine