Informed Surgery

Spinal fusion uses screws, rods and spacers (cages) placed between vertebrae, plus bone graft to help the bones grow together. Many hospitals also use navigation or robots to place screws. Listed alphabetically. No company pays to be listed.

An industry analysis says Medtronic and Globus Medical together account for about 43% of global spine sales, with no other company above 8%. Stryker sold its spinal implant business to VB Spine in early 2025. (ORTHOWORLD.)

Listing a company or product is not an endorsement, and no company pays to be listed. This list may be incomplete. Compiled November 2026 from FDA records, company pages and trade press.

ATEC (Alphatec)

Spine-only portfolio

Products
Implants and approach systems for lumbar fusion, with its own technology platform.
Company
Fast-growing spine-only company; 2025 spine sales up 26% per ORTHOWORLD.

Sources: Company site · ORTHOWORLD

DePuy Synthes (J&J MedTech)

Spine portfolio

Products
Screw-and-rod systems, interbody cages and biologics.

Sources: Company site

Globus Medical (including NuVasive)

Spine portfolio and ExcelsiusGPS robot

Products
Screw-and-rod systems, interbody cages, biologics, and the ExcelsiusGPS robotic navigation platform.
Company
Merged with NuVasive in 2023.

Sources: Company site · ORTHOWORLD

Highridge Medical

Former ZimVie spine business

Company
Privately held company formed from ZimVie's spine assets.

Sources: ORTHOWORLD

Medtronic

Spine portfolio, Infuse bone graft, navigation and robotics

Products
Screw-and-rod systems, cages, StealthStation navigation and Mazor robotics.
Biologics
Infuse Bone Graft (rhBMP-2), approved in February 2026 for one- or two-level TLIF with a cleared cage and screw system.

Sources: FDA PMA P000058/S096 (PDF) · Company site

Orthofix (including SeaSpine)

Spine portfolio and bone growth stimulators

Products
Fixation systems, biologics and bone growth stimulators.
Company
Merged with SeaSpine in 2023.

Sources: Company site

SI-BONE

iFuse implants

Products
Implants for sacroiliac joint fusion; iFuse Granite Onyx, its first compromised-bone product for use outside the pelvis, was cleared in September 2026.

Sources: Becker's Spine

VB Spine

Former Stryker spinal implants

Company
Privately held; bought Stryker's spinal implant business in early 2025. Its implants are paired with Stryker's Mako Spine robot.

Sources: Bone Zone

Other cleared lumbar cages (2026)

Life Spine VersaLift; Spinal Elements Luna Ti; Xenix Medical Lux

What's new
Several smaller companies received 510(k) clearance for expandable or titanium lumbar cages in 2026.

Sources: Becker's list · FDA K250773